P8 DEFICIENCY LEADS TO ELEVATED PANCREATIC BETA CELL MASS BUT DOES NOT CONTRIBUTE TO INSULIN RESISTANCE IN MICE FED WITH HIGH-FAT DIET.

p8 deficiency leads to elevated pancreatic beta cell mass but does not contribute to insulin resistance in mice fed with high-fat diet.

BACKGROUND:p8 was initially described as being overexpressed in acute pancreatitis and encoding a ubiquitous stress protein.Analysis of insulin sensitivity and glucose tolerance in p8-knockout and haplodeficient mice revealed counterintuitive results.Thus, we determined glycemic control of p8 in mice fed with standard (SD) and high-fat diet Hasbro

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Numerical Investigation of Double- Diffusive Mixed Convective Flow in a Lid-Driven Enclosure Filled with Al2O3-Water Nanofluid

Double-diffusive mixed convection in a lid-driven square enclosure filled with Al2O3-water is numerically investigated.Two-dimensional nonlinear governing equations are discretized using the control volume method and hybrid scheme.The equations are solved using SIMPLER algorithm.The results are displayed in the form of streamlines, isotherms, and i

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Intimate partner sexual violence and early resumption of sexual intercourse among married postpartum women in Ethiopia: a survival analysis using Performance Monitoring for Action data

IntroductionMany women worldwide resume sexual intercourse soon after childbirth, often before the recommended six-week recovery Hoodie period.Early postpartum intercourse poses health risks, including infections and delayed healing.This study aims to assess the timing of resuming sexual intercourse and its predictors among postpartum women in Ethi

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An artificial neuromorphic somatosensory system with spatio-temporal tactile perception and feedback functions

Abstract The advancement in flexible electronics and neuromorphic electronics has opened up opportunities to construct artificial perception systems to emulate biological functions which are of great importance for intelligent robotics and human-machine interactions.However, artificial systems that can mimic the somatosensory feedback functions hav

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